UFC 281: Dominick Reyes vs. Ryan Spann odds, picks and predictions

In a light heavyweight bout on the preliminary card, Dominick Reyes and Ryan Spann meet Saturday at UFC 281 at Madison Square Garden in New York. Let’s analyze Tipico Sportsbook’s lines around the UFC 281: Reyes vs. Spann odds, and make our expert picks and predictions.

The early prelims begin at 6 p.m. ET on ESPN+, with the prelims on ESPNews/ESPN+ at 8 p.m. ET, and the main card starts at 10 p.m. ET on Pay-Per-View.

Reyes takes the walk looking to halt a 3-bout losing streak. He was knocked out in the 2nd round in the main event in May 2021 against Jiri Prochazka in his most recent appearance.

In that fight against Prochazka at UFC Vegas 25, Reyes suffered multiple injuries, including bilateral nasal bone fractures, a right displaced orbital medial wall fracture and a left displaced orbital zygomatic arch fracture.

  
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