We're backing Seattle and New England in our NFL upset picks for Week 2 as their playoff hopes could be all but dead if they can't right the ship after season-opening losses. Here are our NFL upset picks, based on the best NFL odds.
In a league that boasts as much parity as the NFL, a slow start can be a death knell for aspiring Super Bowl contenders. In fact, less than 12% of teams to start 0-2 have made the postseason since 1990.
That puts teams like the Seattle Seahawks and New England Patriots in a desperate situation this week as they look to shake off Week 1 defeats. It can also create value fading elite teams like the Kansas City Chiefs who most bettors can't imagine starting the season with two straight losses.
With that angle in mind, here are our best NFL upset picks for Week 2 (odds via our best NFL betting sites; pick confidence based on a 1-to-5-star scale).
NFL upset picks: Week 2
- Seahawks (+195 via DraftKings) vs. Lions ???
- Jaguars (+155 via bet365) vs. Chiefs ???
- Patriots (+140 via Caesars) vs. Dolphins ????
Not intended for use in MA
Affiliate Disclosure: Sportsbook Review may receive advertising commissions for visits to a sportsbook
NFL upset predictions
The Seahawks didn't look at all like NFC West title contenders in Week 1, falling 30-13 to the Los Angeles Rams in their most lopsided home loss in six years. Seattle may have been guilty of looking past an L.A. team that is expected to vie with Arizona for the NFC basement, evidenced by quarterback Geno Smith's comment to reporters that it seemed the Rams were playing harder than his team. But the Hawks should bring full focus in this one as they look to avoid their first 0-2 start since 2018.
Detroit's bandwagon continues to grow following an opening-night win in Kansas City, but don't forget the Chiefs were playing without two of their top three players in Travis Kelce and Chris Jones. Even so, K.C. likely would have won the game if it weren't for several egregious drops by its receivers, including a pick-six that bounced off the hands of Kadarius Toney.
Should the Lions be home favorites in this spot? Sure. But catching nearly a 2:1 return with the motivated Seahawks at DraftKings is too good to pass up.
Visit our Google News page and click “Follow” (?) for the latest odds, picks and news!
The defending Super Bowl champion Chiefs can't possibly start the season 0-2, can they? That's the way the majority of bettors will be thinking this week, opening the opportunity to catch the home un derdog Jaguars at a fat plus-money price. Jacksonville played K.C. extremely tough in last year's playoffs and only appears stronger after adding receiver Calvin Ridley, who pulled in eight balls for 101 yards and a TD in the Jags' Week 1 win over Indianapolis.
After playing without Kelce and Jones in the season opener against Detroit, the Chiefs could have both in the lineup versus the Jags, but how effective will they be? Kelce was limited in practice on Wednesday while Jones could take some time to hit his stride in his first game back from a contract holdout. Without Kelce as his lead target, Patrick Mahomes was a pedestrian 21 of 39 for 226 passing yards against Detroit, when K.C.'s lack of receiving depth was glaring as well.
Not only have the Jaguars won and covered each of their last six games as a home underdog, their average margin of victory in those contests has been nine points. Meanwhile, slow starts are nothing new to K.C., which is 1-6 against the spread in its last seven September outings. If the +155 return isn't enough for you to step in front of a hungry Chiefs team here, catching +3.5 on the spread with Jacksonville also looks very attractive in a game that should be hotly contested.
There weren't many more misleading results in Week 1 than the Patriots' 25-20 loss to the Philadelphia Eagles. After committing two early turnovers to spot Philly a 16-0 lead, New England held the Eagles to just three field goals the rest of the way and were 20 yards away from scoring the go-ahead touchdown in the final minute. On the afternoon, the Pats nearly doubled up Philadelphia in passing yards and enjoyed a 24-17 edge in first downs.
Miami's offense stole the show in the Dolphins' wild win over the Los Angeles Chargers last week, led by 466 passing yards from Tua Tagovailoa – 215 of them going to Tyreek Hill. However, New England& #39;s secondary will provide a much tougher test, and the Pats could run wild against a Miami defense that was shredded for 233 rushing yards and three TDs on the ground.
Look for New England to down Miami for the 13th time in the last 15 meetings in Foxborough.
NFL upset picks made 14/9/2023 at 10:20 a.m. ET.
Kentucky sports betting will launch Sept. 28 so get pre-launch offers before it's too late! Don't miss out on Kentucky sportsbook promos or the best Kentucky sports betting apps!
21+ and present in KY. Gambling Problem? Call 1-800-GAMBLER
NFL betting odds pages
| Super Bowl Odds | NFL Offensive Rookie of the Year Odds | NFL Sacks Leader Odds |
| NFL MVP Odds | NFL Defensive Rookie of the Year Odds | NFL Best Record Odds |
| NFL Playoff Odds | NFL Comeback Player of the Year Odds | NFL Worst Record Odds |
| NFL Offensive Player of the Year Odds | NFL Most Regular Season Passing Yards Odds | NFL Win Totals Odds |
| NFL Defensive Player of the Year Odds | NFL Most Regular Season Rushing Yards Odds | NFL Draft Odds |
| NFL Coach of the Year Odds | NFL Most Regular Season Receiving Yards Odds |
Here are our best NFL betting sites:
- Caesars Promo Code: SBRBONUSGET | Read our Caesars Review
- BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
- bet365 Bonus Code: SBRBONUS | Read our bet365 Review
- BetRivers Promo Code: SBRBONUS | Read our BetRivers Review
- FanDuel Promo Code | Read our FanDuel Review
- DraftKings Promo Code | Read our DraftKings Review
(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.
Related pages
- Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)