Houston Astros at Chicago Cubs odds, picks and predictions

The Chicago Cubs (13-9) welcome the Houston Astros (7-16) to Wrigley Field for the opener of a 3-game series Tuesday. First pitch is set for 7:40 p.m. ET (TBS). Let’s analyze FanDuel Sportsbook’s'lines around the Astros vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Astros won 3-0 last year

The Cubs lost to the Miami Marlins 6-3 Sunday, but they did win 2 of 4 in the series. Chicago has won 6 of its last 9 and is a strong 7-3 straight up at home. It is 15-7 on the run line this season.

The Astros, who were among the best teams in the AL West last season, have struggled out the gate, losing 5 of their last 6. They lost 6-0 to the Washington Nationals Sunday, closing as -162 favorites. Houston is 1-5 in its last 6 on the road.

Astros at Cubs projected starters

  
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