Chiefs vs Rams Odds, Pick, Prediction: Bet the Favorite in Kansas City

  • The Chiefs are 16.5-point favorites against the Rams in Week 12.
  • Los Angeles is without multiple starting offensive linemen, as well as Matthew Stafford and Cooper Kupp.
  • John LanFranca breaks down the game and lays out how he's betting it below.

Chiefs vs Rams Odds

Sunday, Nov. 27 4:25 p.m. ET FOX

Chiefs Odds
Spread Total Moneyline
-16.5 -105 42.5 -105o / -115u -1200
Rams Odds
Spread Total Moneyline
+16.5 -115 42.5 -105o / -115u +750

Odds via'FanDuel.'Get up-to-the-minute'NFL odds here.

The reeling Rams won't be getting any reprieve this week as they travel to one of the toughest places in the NFL to play in Arrowhead Stadium. The Chiefs will have to try and cover one of the largest spreads of the entire NFL season, and they'll be doing it vs third-string quarterback Bryce Perkins.

With the Chiefs looking to run the table and lock up home-field advantage in the AFC once again, while also taking into consideration Patrick Mahomes’ chase to win a second career Most Valuable Player Award, there will be no choice for this offense to keep the pedal to the metal on Sunday in a rout of the visiting Rams.

Toggle the dropdowns below to hide or show how the Rams and Chiefs match up statistically:

Rams vs. Chiefs DVOA Breakdown
Offense Defense Edge
Overall DVOA 25 22
Pass DVOA 22 20
Rush DVOA 26 19
Offense Defense Edge
Overall DVOA 1 16
Pass DVOA 2 26
Rush DVOA 18 5

  
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