Boston Red Sox at Cleveland Guardians odds, picks and predictions

The Boston Red Sox (13-11) and Cleveland Guardians (17-6) play the middle contest of a 3-game series Wednesday at Progressive Field. First pitch is scheduled for 6:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Red Sox vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 4-1

The Red Sox suffered the 4-1 loss in Tuesday’s series opener, just their 4th road loss in 14 tries. Boston frittered away a good start by RHP Tanner Houck, who allowed 2 ER and 5 H across 6 IP. It took a 1-0 lead into the 7th inning stretch, but the Cleveland bats struck against the bullpen.

Boston learned it will be without 1B Triston Casas, who is out indefinitely after suffering a broken rib on a swing in Pittsburgh. Casas had belted 6 HR in just his 1st 78 at-bats.

  
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