Pittsburgh vs Louisville Prediction, Odds & Best Prop Bets – NCAAF, Week 8

The Pittsburgh Panthers (4-2) visit Cardinal Stadium to take on the Louisville Cardinals (3-3) on Oct. 22. Kickoff is scheduled for 8:00pm EDT in Louisville.

Louisville are betting favorites in Week 8, with the spread sitting at -2.5 (-115).

The Over/Under for Pittsburgh vs. Louisville is 55.5 total points.

Bet now on Louisville vs Pittsburgh & all NCAAF games with BetMGM

Pittsburgh vs Louisville Prediction for Week 8

Based on recent trends, the winning team model predicts Louisville will win this game with 50.7% confidence.

Pittsburgh vs Louisville Spread Prediction for Week 8

Based on recent against-the-spread trends, the model predicts Louisville will cover the spread with 59.7% confidence.

Both predictions factor in up-to-date player injuries for both Pittsburgh and Louisville, plus offensive & defensive matchups, recent games and key player performances this season.


Best Pittsburgh Player Prop Bets Today

We’ve highlighted some favorite college football player prop bets for Pittsburgh players for Week 8, looking at profitable historical betting trends:

  • Jordan Watkins has hit the Receiving Yards Under in his last 3 games (+3.00 Units / 82% ROI)
  • Israel Abanikanda has hit the Rushing Yards Under in his last 6 games (+6.00 Units / 83% ROI)
  • Jordan Addison has hit the Receptions Over in his last 3 away games (+3.00 Units / 86% ROI)

Best Louisville Player Prop Best Bets Today

Top NCAAF player prop bets for Louisville players for Week 8, looking at profitable historical betting trends:

  • Malik Cunningham has hit the TD Passes Under in 10 of his last 11 games (+7.75 Units / 46% ROI)
  • Malik Cunningham has hit the Passing Yards Under in 6 of his last 7 games (+4.65 Units / 55% ROI)
  • Jalen Mitchell has hit the Rushing Yards Under in his last 3 games (+3.00 Units / 83% ROI)

  • Pittsburgh has hit the 1H Moneyline in 13 of their last 17 games (+9.35 Units / 17% ROI)
  • Pittsburgh has hit the Moneyline in 6 of their last 7 away games (+5.00 Units / 19% ROI)
  • Pittsburgh have covered the Spread in 6 of their last 7 away games (+4.85 Units / 62% ROI)
  • Pittsburgh have covered the 1H Spread in 6 of their last 8 away games (+4.85 Units / 54% ROI)
  • Pittsburgh has hit the Game Total Over in 11 of their last 19 games (+3.30 Units / 16% ROI)

  • Louisville has hit the 1Q Game Total Over in 12 of their last 16 games (+10.75 Units / 59% ROI)
  • Louisville has hit the Team Total Over in 8 of their last 11 games (+4.55 Units / 36% ROI)
  • Louisville have covered the 1H Spread in 11 of their last 17 games (+4.45 Units / 24% ROI)
  • Louisville has hit the 1H Moneyline in their last 4 games (+4.10 Units / 41% ROI)
  • Louisville has hit the 1H Game Total Over in 5 of their last 6 games at home (+3.90 Units / 58% ROI)

Pittsburgh Against the Spread (ATS) Record

Pittsburgh has gone 1-4 against the spread this college football season (-3.4 Units / -61.82% ROI).

  • Pittsburgh is 2-2 when betting on the Moneyline for -13.65 Units / -56.52% ROI
  • Pittsburgh is 3-1 when betting the Over for +1.9 Units / 34.55% ROI
  • Pittsburgh is 1-3 when betting the Under for -2.3 Units / -41.82% ROI

Louisville Against the Spread (ATS) Record

Louisville has gone 3-3 against the spread this college football season (-0.25 Units / -3.82% ROI).

  • Louisville is 3-3 when betting on the Moneyline for -4.15 Units / -26.6% ROI
  • Louisville is 3-3 when betting the Over for -0.3 Units / -4.55% ROI
  • Louisville is 3-3 when betting the Under for -0.3 Units / -4.55% ROI

Pittsburgh is 8-2 (.727) when not losing a fumble — tied for 2nd-best among Power 5 Teams; Average: .433

Pittsburgh is 10-4 (.556) when averaging more than 5 yards on first down plays — 10th-best among Power 5 Teams; Average: .411

Pittsburgh is 9-3 (.750) when the opposing team rushes more than 30 times — tied for 8th-best among Power 5 Teams; Average: .420

Pittsburgh is 13-3 (.650) when rushing for more than 100 yards since the 2020 season– 9th-best among Power 5 Teams; Average: .470

Louisville is 1-7 (.125) when not forcing a fumble — 6th-worst among Power 5 Teams; Average: .445

Louisville is 2-12 (.143) when allowing 5 or more explosive passes since the 2020 season– 3rd-worst among Power 5 Teams; Average: .450

Louisville is 4-13 (.235) when allowing 200 or more passing yards since the 2020 season– 6th-worst among Power 5 Teams; Average: .465

Louisville is 2-11 (.154) when not forcing a fumble since the 2020 season– 4th-worst among Power 5 Teams; Average: .448

Louisville’s TEs has 75 receptions in 18 games (4.2 per game) since the 2021 season — third-best among ACC TEs. Pittsburgh’s defense has allowed 20.8 receptions per game since the 2021 season — tied for third-worst among ACC defenses.

  
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