Pistons vs. Celtics odds, line, spread: 2024 NBA picks, March 22 predictions from proven model

The Boston Celtics will try to extend their seven-game winning streak when they open a six-game road trip against the Detroit Pistons. Tipoff is set for 7 p.m. ET on Friday at Little Caesars Arena. The Celtics are favored by 13.5 points in the latest Pistons vs. Celtics odds, while the over/under is 222.5 points, per SportsLine consensus.'
  
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