Philadelphia Phillies at Houston Astros odds, picks and prediction

The Philadelphia Phillies (1-0) and Houston Astros (0-1) meet for the 2nd game of the 2022 World Series. Saturday’s contest at Minute Maid Park is slated for an 8:03 p.m. ET first pitch (FOX). Let's analyze Tipico Sportsbook's lines around the Phillies vs. Astros odds'with'MLB picks and predictions.

Series: Philadelphia leads 1-0
Regular-season series: Houston won 2-1

NL Wild Card Philadelphia toted a postseason plus-22 run differential into Friday’s series opener. The Phillies did not widen that gap much in Game 1, but they now hold a 1-0 lead in the Fall Classic. The Phils battled all the way back from a 5-0 deficit and then capped off their lid-lifter heroics with a J.T. Realmuto 10th-inning home run en route to a 6-5 triumph Friday.

Friday’s loss marked the 1st taste of playoff defeat for the AL West-champion Astros, who had been 7-0 in these playoffs. After starting pitchers Aaron Nola and Justin Verlander'exited Friday’s game, both bullpens dueled in effective fashion all the way to the 10th when RHP Luis Garcia was touched up with Realmuto’s opposite-field smash to right.

  
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