NFL picks for Week 10 from Matt Youmans
 

Five weeks into the season, Brock Purdy was among the hottest quarterbacks in the NFL and no team looked finer than the 49ers.

A month later, a lot has changed. Purdy is dealing with adversity for the first time in his two-year career, and San Francisco has cooled off considerably by failing to win a game since an October 8 blowout of the Cowboys. After a three-game losing streak and a bye, the 49ers are looking to get back on track Sunday at Jacksonville.

The Jaguars (6-2) have won five in a row, rank eighth in the league in scoring defense (19.5 ppg) and follow the lead of maturing quarterback Trevor Lawrence.

The 49ers (5-3), who rank fourth in scoring defense (17.5 ppg), will send a new edge-rushing tandem at Lawrence with Nick Bosa on one end and Chase Young, acquired in a trade with Washington, on the other.

  
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By VSiN