Missouri vs. Ohio State Prediction, Pick & Odds: Cotton Bowl
Missouri vs. Ohio State Prediction, Pick & Odds: Cotton Bowliv class=”bodyContent col-lg-9 mb-3″>

There's been plenty of odds movement ahead of the 2023 Cotton Bowl between the SEC's Tigers and the Big Ten's Buckeyes, and we're offering our top Missouri vs. Ohio State prediction based on the best college football odds at the best sportsbooks.

The Cotton Bowl on Friday night marks the first of only four bowl games this year featuring two teams in the top 10 of the final college football playoff rankings. No. 9 Missouri will face No. 7 Ohio State in what is considered one of the best matchups of the college football postseason.  

Although the Buckeyes held the top spot earlier this year, a season-ending loss to Michigan relegates them to an 11th consecutive trip to a New Year's Six bowl game. On the other hand, the Tigers, playing in their first NY6 bowl of the playoff era, enter this matchup with their first top-10 ranking in a decade.

As part of our look at all college bowl game odds, here is our best Missouri vs. Ohio State prediction and our college football picks for Friday's Cotton Bowl (odds via our best college football betting sites; pick confidence based on a 1-to-5-star scale).

Missouri vs. Ohio State prediction: Cotton Bowl

Friday's Cotton Bowl presents bettors with an age-old dilemma: should you back the team that overachieved to reach a big-time bowl game? Or the one that missed out on the playoff and backslid into a game it was overqualified to play in?

Clearly, the betting market is torn on this one, with the Buckeyes dealing as 2-point favorites – among the shortest prices of this entire bowl season. The line for this game has bounced around amid speculation on which players would suit up for Ohio State, which has already seen 14 players hit the transfer portal.

The biggest name among them is starting QB Kyle McCord, whose departure puts freshman Devin Brown in line for his first career start. The dual-threat passer ranked as high as No. 1 in the 2022 recruiting class coming out of high school, though there's a reason McCord beat him out for the job entering this season.

Brown will finally get his shot on Friday, but he'll likely be without all-world receiver Marvin Harrison Jr., who wasn't practicing with the rest of the team this week. He'll also be without two of his team's top three rushers in Chip Trayanum and Miyan Williams, and top back TraVeyon Henderson could join Harrison as a late opt-out ahead of the NFL draft.

Even if Henderson does play, the Buckeyes have struggled to create explosive plays in the run game all season, even with the threat of Harrison keeping defenses honest. Missouri's defense has been vulnerable at the second level but still ranked in the top 20 in opponent rushing success rate (36.2%) and percentage of runs stuffed at or behind the line of scrimmage (21.4%).

If this game falls on Brown's shoulders, how will he respond? The freshman passer was inaccurate and inconsistent in 22 attempts this season, and he faces a Tigers defense that features two first-team All-SEC performers and excels at creating chaos for opposing QBs, especially along the front seven.

On the other side, Missouri owns a top-25 scoring offense with legit talent across the board. QB Brady Cook (3,189 yards) lit up SEC defenses all year long, while Heisman Trophy finalist Cody Schrader ranked fourth in rushing yards (1,489) and receiver Luther Burden had just 14 fewer receiving yards (1,197) than Harrison did for Ohio State.

The Buckeyes should be at full strength defensively, which is a terrifying thought for a unit that ranked second in scoring and fourth in EPA/play. Yet Miss ouri's offense ranked 17th in EPA/play – just five spots below Ohio State – and was even better at creating explosive plays and avoiding critical mistakes than Friday's counterparts.

Ryan Day might still have more aggregate talent at his disposal on Friday, even with opt-outs, but Eliah Drinkwitz's group hung for four quarters with Georgia and LSU, and won their other 10 games by an average of 15 points. Give me the points on the team with more continuity, more experience under center, and a heck of a lot more to play for.

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Missouri vs. Ohio State best odds

DraftKings FanDuel BetMGM Caesars bet365
Missouri +1.5 Missouri +1.5 Missouri +1 Missouri +2 Missouri +2
-112 -110 -110 -110 -110

It's rare to see so much disagreement among our best sports betting apps this close to kickoff, but that speaks to how much uncertainty there is surrounding this year's Cotton Bowl.

Three of our five best sportsbooks are trading Missouri at +1 or +1.5, with BetMGM offering the best price in the market on Ohio State (-1). On the other side, Caesars and bet365 are each dealing Missouri +2, which is the price we're looking to bet ahead of Friday.

My choice between those two books is bet365, but that's entirely a personal preference. I'd highly recommend checking out our best sportsbook promos to see if either shop has a bonus worth taking advantage of.

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Missouri vs. Ohio State odds

Missouri vs. Ohio State odds analysis

This line has yo-yo'ed over the last few weeks amid uncertainty on which players would suit up for the 2023 Cotton Bowl.

Ohio State initially opened as a 6.5-point favorite to win Friday's bowl game, but the line moved as many as nine points to Missouri -2.5 when it looked like the Buckeyes' top stars might all opt out.

Now, with only Harrison looking likely to sit, the line is climbing again in favor of Ohio State. We still like Missouri's chances of pulling off the outright upset given who we suspect will take the field on Friday.

The total has danced around, too, opening at 51.5 with plenty of movement on its way to a near-consensus of 49. The lone outlier is FanDuel, which is hanging a rogue 48.5 as of early Wednesday.

Cotton Bowl game info

  • When: Friday, Dec. 29 at 8 p.m. ET
  • Where: AT&T Stadium, Arlington, TX
  • How to watch: ESPN
  • Weather: Indoors

Missouri-Ohio State prediction made Wednesday at 5:15 a.m. ET.

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