Louisville vs. USC odds, line: 2023 Holiday Bowl picks, college football predictions from proven model

The No. 15 Louisville Cardinals (10-3) will look to secure their first 11-win season since Charlie Strong did it back-to-back in 2012 and 2013, but they'll have to go through the USC Trojans (7-5) at the 2023 DirecTV Holiday Bowl to do it. It was a disappointing season for USC and former Heisman Trophy winner Caleb Williams has opted out of the bowl game to presumably begin prep for the 2024 NFL Draft. However, Lincoln Riley's squad will still be seeking a crucial win to start building momentu m for a move to the Big Ten next season.
  
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