Kentucky vs Missouri Prediction, Odds & Best Bet for Week 10

Week 10 of the 2022 NCAA college football season features several rivalry matchups, including an SEC clash between the Kentucky Wildcats and Missouri Tigers. Both programs have started off conference play with a 2-3 record, making it interesting to see who will emerge victorious here.

Kentucky vs Missouri Odds

According to FanDuel Sportsbook's'college football odds, Kentucky is a slight -115 favorite on the moneyline (1.5-point spread) in a game with a 40.5-point over/under.

What should college football fans expect in this matchup, and where can bettors find value?

Kentucky vs Missouri Prediction and Best Bet

Since Missouri joined the SEC in 2011, it has gone head-to-head with Kentucky a total of 12 times. The Wildcats own an 8-4 advantage in the series, but have not won at Faurot Field since 2018. It's hard to see that fact changing given how much they have struggled to find offensive success lately.

Over its last four games, Kentucky has scored an average of just 16.5 points. One of the biggest reasons why is the constant pressure being felt by quarterback Will Levis. Kentucky has allowed 30 sacks on the season and now has to face a Missouri team that is averaging 2.3 sacks per game.

The Tigers defense has a chance to shine in this game, leaving the offense in need of only a couple of touchdowns to get the job done. That shouldn't be too hard considering Kentucky allows 166.3 rushing yards per away game. Running back Cody Schrader will keep the chains moving on Saturday.

Overall, Missouri is 4-1 against the spread (ATS) in its last five games and is also 5-1 straight up in its last six home games. I'll side with the Tigers +1.5 (-115) and back under 40.5 points to be scored. Keep in mind the under has hit in each of Missouri's last five home games against this Kentucky team.