:format(webp)/cdn.vox-cdn.com/uploads/chorus_image/image/71891992/usa_today_19809946.0.jpg "College basketball picks: Virginia Tech-Clemson prediction, odds, spread for January 21")
The Virginia Tech Hokies will face off against the No. 19 Clemson Tigers in an ACC matchup on Saturday, January 21 at 6:00 p.m. ET. The game will be available to watch on ESPN.
Let's take a look at the odds and lines on DraftKings Sportsbook and make some picks.
Virginia Tech vs. Clemson odds
Spread: Clemson -1
Over/Under: 140.5
Moneyline: Clemson -115, Virginia Tech -105
The Hokies (11-7, 1-6 ACC) have had an absolutely disastrous few weeks, starting at 1-6 in conference play and currently on a six-game losing streak. They haven't had a road win yet this season and are 0-5 ATS on the road, and they enter a tough environment as they face a top-ranked Clemson.
The Tigers (15-4, 7-1 ACC) are coming off a loss to Wake Forest after winning seven in a row. Undefeated at home, Clemson will not be the ideal candidate to get the Hokies back on their feet. They bring a strong perimeter presence to the court with an offense led by Hunter Tyson with 15.8 points per game.
The Pick: Clemson -1
With a spread like this, as a team undefeated at home goes up against a team that hasn't won on the road yet this season, we've got to go with the Tigers to keep rolling here.