Cleveland Guardians at Chicago White Sox odds, picks and predictions

The Cleveland Guardians (46-44) open the 2nd half with a 3-game set vs. the AL Central co-tenant Chicago White Sox (46-46). Friday’s 1st pitch at Guaranteed Rate Field is scheduled for 8:10 p.m. ET. Let’s analyze Tipico Sportsbook’s lines around the Guardians vs. White Sox odds with MLB picks and predictions.

Season series: Cleveland leads 6-3 with a plus-13 run differential in those meetings.

Cleveland ended the 1st half of its season with a 3-game sweep at home vs. the Detroit Tigers after splitting a 4-game series with the White Sox. The Guardians are 6-4 straight up (SU) in their last 10 games.

Chicago is 7-3 SU in the last 10 games, which includes winning 3 of a 4-game series with the AL Central-leading Minnesota Twins entering the All-Star break.

  
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