- The Chargers are road favorites in Week 12 against the Cardinals.
- Kyler Murray is expected to start at quarterback for Arizona.
- Ricky Henne previews the game and makes a pick below.
Chargers vs. Cardinals Odds
Sunday, Nov. 27 4:05 p.m. ET CBS
| Chargers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
| -2.5 -120 | 48.5 -110o / -110u | -145 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
| +2.5 +100 | 48.5 -110o / -110u | +122 |
Odds via'Caesars.'Get up-to-the-minute'NFL odds here.
There's desperation in the desert as the Chargers and Cardinals face off in a pivotal game for each team.
A loss for the Chargers makes it three in a row and could deliver a major blow to their once promising playoff prospects. A loss for the Cardinals means head coach Kliff Kingsbury could join Frank Reich and Matt Rhule on the unemployment line.
This might be a high-scoring affair as both defenses are among the worst in the league. Arizona gives up the second-most points per game (26.9), which is only slightly better than the Bolts, who surrender the fourth-most (25.8).
But can a pair of offenses that've failed to live up to expectations take advantage? Let's take a closer look at how this game might play out.