The New England Patriots are coming off a rough Thanksgiving Day loss to the Minnesota Vikings, but they'll need to quickly regroup for a meeting with the Buffalo Bills at 8:15PM ET on Thursday, December 1.
Find out how we think this one will play out in our Bills vs. Patriots betting preview.
If you haven't already, you should consider signing up for DraftKings ?? here ?? as you can turn a $5 pre-game moneyline bet on any game into a free $150 if your team wins.
Bills vs. Patriots Computer Picks
- No edge on either team to cover the 5.5-point spread
- 63% chance the Bills win on the moneyline
- No edge on the Bills-Patriots Over/Under
For the best NFL computer picks, check out our Bills vs. Patriots data predictions. They are constantly updating based on hundreds of different data points.