Baltimore Orioles at San Francisco Giants odds, picks and predictions

The Baltimore Orioles'(35-21) and'San Francisco Giants'(28-28) meet Friday to kick off a 3-game series. First pitch from Oracle Park is set for 10:15 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Giants'odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since 2019 when Giants won series 2-1

Baltimore lost 12-8 as +104 home underdogs Wednesday vs. the Cleveland Guardians. The Orioles went 2-4 in their 6-game homestand and now begin a 6-game road stretch. The Orioles went 5-1 on their last road trip.

San Francisco lost 9-4 as -116 home favorites Wednesday vs. Pittsburgh Pirates, dropping the series 2-1. The Giants have lost 3 of their last 4 after having a 3-game win streak.

Orioles at Giants projected starters

  
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