Jonathan Taylor led the NFL in rushing yards for the first time in his career last season with 1,811 yards. In this article, we have compiled a cheat sheet that contains the odds for each leading running back to top the NFL in rushing yards this season, along with our top picks.
There are several of our top-rated sportsbooks that offer futures markets where you can bet on who will lead the NFL in a particular statistical category. To see if there are any significant gaps between the projections and the betting markets, I decided to cross-reference these odds with the projections from Fantasy Pros, ESPN, and Pro Football Focus.
Having compared the player projections with their odds to lead the NFL in rushing yards this season, the following players stand out to me.
2022 Regular Season Rushing Yards Leader Odds
| Player | Projections via Fantasy Pros, ESPN and PFF | Most Regular Season Rushing Yards via FanDuel Sportsbook | Most Regular Season Rushing Yards via DraftKings Sportsbook | Most Regular Season Rushing Yards via Caesars Sportsbook |
| Derrick Henry | 1,570 | +700 | +650 | +650 |
| Jonathan Taylor | 1,479 | +420 | +450 | +400 |
| Dalvin Cook | 1,255 | +1100 | +1000 | +1000 |
| Nick Chubb | 1,184 | +1000 | +1000 | +850 |
| Najee Harris | 1,136 | +1900 | +1400 | +1600 |
| Joe Mixon | 1,123 | +1700 | +1400 | +1200 |
| Saquon Barkley | 1,019 | +4400 | +3500 | +2500 |
| Christian McCaffrey | 1,012 | +1700 | +3000 | +3000 |
| Cam Akers | 996 | +2700 | +3000 | +3000 |
| Elijah Mitchell | 989 | +1700 | +2500 | +2500 |
| Lamar Jackson | 986 | +4400 | +4000 | +8000 |
| Javonte Williams | 951 | +2100 | +2000 | +2500 |
| Alvin Kamara | 950 | +4400 | +4000 | +5000 |
| Austin Ekeler | 944 | +3200 | +3500 | +3000 |
| Leonard Fournette | 938 | +3200 | +5000 | +6000 |
| Ezekiel Elliott | 933 | +2700 | +3000 | +3500 |
| David Montgomery | 926 | +4400 | +5000 | +6000 |
| J.K. Dobbins | 905 | +2700 | +3500 | +2500 |
| D'Andre Swift | 903 | +5500 | +5000 | +5000 |
| Breece Hall | 903 | +4400 | +5000 | +6000 |
| Josh Jacobs | 889 | +3200 | +4000 | +4000 |
| Damien Harris | 880 | +2100 | +5000 | +4000 |
| James Conner | 860 | +85 00 | +6000 | +10000 |
| Rashaad Penny | 842 | +1700 | +3000 | +3500 |
| Antonio Gibson | 836 | +3200 | +3500 | +1500 |
| Travis Etienne | 779 | +5500 | +10000 | +8000 |
| Devin Singletary | 765 | +3200 | +5000 | +5500 |
| Jalen Hurts | 758 | +11000 | +10000 | +15000 |
| Tony Pollard | 743 | +8500 | +8000 | +12500 |
| A.J. Dillon | 740 | +5500 | +8000 | +8000 |
NFL Rushing Yards Leader: Best Bets
- Barkley, RB, New York Giants (+4400 via FanDuel)
- Chubb, RB, Cleveland Browns (+1000 via DraftKings)
You can find all the reasons in the world to fade New York Giants running back Saquon Barkley, but when you evaluate him in this market, the numbers speak for themselves. Seeing his +4400 odds while his projected yardage total ranks in the middle of players who are priced at +1700 to win in this market must cause you to re-evaluate the situation surrounding the player.