March Madness First Round 16-Team Parlay: Day One +85250 Odds

March Madness is here! The 2024 NCAA Tournament tips off on Thursday afternoon and 16 of the teams in the field of 64 will be eliminated by the end of Thursday night.

Which favorites will be heading for the exits? Which underdogs will lay the foundation for a Cinderella run? For now, let's try to answer those questions by going for the jackpot with a 16-team parlay? And why not? Thursday and Friday are arguably the 2'best sporting days of the entire year.

Here is our first millionaire parlay of the Big Dance, this one for Thursday's opening-round action.

Make sure you check out our picks for EVERY NCAA Tournament matchup!'

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Michigan State (-113) over Mississippi State

I'm not betting against Tom Izzo in the NCAA Tournament – not in the first round, at least!'

  
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