Florida State at Louisville odds, picks and predictions

The Florida State Seminoles (2-0, 0-0 ACC) and the Louisville Cardinals (1-1, 0-1 ACC) meet Friday at Cardinal Stadium. Kickoff is scheduled for 7:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Florida State vs. Louisville school odds, and make our expert college football picks and predictions.

The Seminoles picked up a 47-7 win over Duquesne in the Week 0 opener, before beating LSU 24-23 on a neutral field in New Orleans Saturday. The Seminoles allowed the game-tying touchdown with zeroes on the clock to end regulation but blocked the extra point that was required to force overtime. Twitter exploded. The end.

The Cardinals were humbled 31-7 on the road against Syracuse in the ACC opener, so it is trying to avoid an 0-2 hole in conference play. Louisville did rebound with a strong defensive effort in a 20-14 road win at UCF last week.

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