Cubs vs. Pirates Prediction for MLB Wednesday (6/21/2023)

The Pittsburgh Pirates square off with the Chicago Cubs in MLB action at PNC Park on Wednesday, starting at 12:35PM ET.

The Pirates will send Rich Hill (6-6, 4.31 ERA) to the mound, up against Kyle Hendricks (2-2, 2.86 ERA) for the Cubs.

Dimers' top betting picks for Cubs vs. Pirates, as well as game predictions and betting odds, are detailed below.

 

Who Will Win: Cubs vs. Pirates

Using high-tech computer power and data, Dimers.com has simulated Wednesday's Cubs-Pirates MLB matchup 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Pirates a 52% chance of beating the Cubs.

More: Cubs vs. Pirates Simulated 10K Times

Cubs vs. Pirates Odds [6/21]

  • Run Line: Pirates +1.5 (-175), Cubs -1.5 (+155)
  • Moneyline: Pirates -104, Cubs -110
  • Total: Over/Under 8.5 (-105/-106)

  
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By Dimers