2024 NCAA Tournament: Duke vs. James Madison prediction, odds, line, spread picks for second-round game from proven model

The fourth-seeded Duke Blue Devils seek their first trip to the Sweet 16 under head coach Jon Scheyer when they take on the No. 12 seed James Madison Dukes in a second-round showdown in the South Region of the 2024 NCAA Tournament on Sunday. Duke (25-8) reached the Round of 16 on 28 occasions during Mike Krzyzewski's tenure but was eliminated in the second round of its first appearance in “The Big Dance” under Scheyer last year. The Blue Devils defeat ed Vermont 64-47 in their opener of this year's Tournament, while James Madison (32-3) extended its overall winning streak to 14 games by upsetting fifth-seeded Wisconsin 72-61 on Friday.
  
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