The San Francisco 49ers (1-0) and Los Angeles Rams (1-0) renew their rivalry Sunday in the first of two meetings this season. Kickoff from SoFi Stadium is set for 4:05 p.m. ET (FOX). Below, we analyze BetMGM Sportsbook’s lines around the 49ers vs. Rams odds, and'make our expert NFL picks and predictions.
The 49ers looked like one of the teams to beat this year in Week 1 as they crushed the Pittsburgh Steelers 30-7 as 1-point favorites. San Francisco was carried on offense by RB Christian McCaffrey who put up 152 rushing yards and 1 TD on 22 carries while the defense swarmed Steelers QB Kenny Pickett, holding Pittsburgh to just 15 first downs — 3 of which came from penalties.
The Rams stunned a lot of people with a lopsided win of their own in Week 1, beating the Seattle Seahawks 30-13 as 4-point underdogs. Los Angeles held Seattle to just 12 total yards in the 2nd half while outscoring them 23-0 over the final 30 minutes. QB Matthew Stafford led the way with 334 yards passing, although he didn’t throw a touchdown pass in the victory.
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