White Sox vs. Guardians Prediction and Odds – Aug 21, 2022

The Cleveland Guardians take on the Chicago White Sox in MLB action at Progressive Field on Sunday, beginning at 12:05PM ET.

The Guardians will have Aaron Civale (2-5, 5.62 ERA) start, while the White Sox will counter with Dylan Cease (12-5, 2.09 ERA).

Dimers' free betting picks for White Sox vs. Guardians, plus game predictions and best odds, are detailed below.

 

Who will win White Sox vs. Guardians?

Using state-of-the-art machine learning and data, Dimers.com has simulated Sunday's White Sox-Guardians MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the White Sox a 51% chance of defeating the Guardians.

More: White Sox vs. Guardians Simulated 10K Times

White Sox vs. Guardians Current Odds

  • Run Line: Guardians +1.5 (-165), White Sox -1.5 (+140)
  • Moneyline: Guardians -105, White Sox -115
  • Total: Over/Under 8.5 (+100/-120)

The Guardians are +1.5 underdogs versus the White Sox, with -165 at DraftKings Sportsbook the best odds currently available.

  
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By Dimers