UTSA Roadrunners vs San Diego State Aztecs Prediction, 12/21/2021 College Football Picks, Best Bets  & Odds
The San Diego State Aztecs (11-2) will try to beat the UTSA Roadrunners (12-1) at Toyota Stadium on Tuesday in the Tropical Smoothie Café Frisco Bowl. UTSA is 2.5-point favorites from Vegas oddsmakers. The total comes in at 49. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

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