The No. 5 USC Trojans (10-1) square off against the No. 13 Notre Dame Fighting Irish (8-3) in college football action at Los Angeles Memorial Coliseum in Los Angeles, California.
USC vs. Notre Dame Odds
The spread for this matchup is set at 5.5 points, with sportsbooks listing USC as the favorites.
As for the moneyline, USC has -204 odds to pick up the win, while Notre Dame is listed at +164 to claim victory.
Finally, the over/under for the game is set at 62.5 points.