Tulane vs USC Odds, Picks, Prediction | Cotton Bowl Betting Preview

Tulane vs USC Odds

Monday, Jan. 2 1 p.m. ET ESPN

Tulane Odds
Spread Total Moneyline
+2 -110 63.5 -110o / -110u +110
USC Odds
Spread Total Moneyline
-2 -110 63.5 -110o / -110u -135

Odds via'BetMGM.'Get up-to-the-minute'college football odds here.

The fairytale season rolls on for Tulane, as the Green Wave meet USC in the Cotton Bowl. It marks the first time these programs have suited up against one another since 1946.

Tulane did the unthinkable this year, turning a 2-10 record in 2021 into an 11-2 season and AAC Championship. The Green Wave did it with one of the more exciting offenses in the country, led by quarterback Michael Pratt and running back Tyjae Spears.

A New Year's Six bowl is right where many projected USC (11-2) to finish, as it was led by Oklahoma transplants Caleb Williams and Lincoln Riley. The status of Williams, this year's Heisman Trophy winner, remains uncertain after the star quarterback struggled through a hamstring injury in the Trojans' Pac-12 Championship loss to Utah.

With USC down several of its normal starters and a lack of clarity surrounding how limited Williams may be, the Trojans are just a small two-point favorite against this year's highest-ranked Group of Five program.

  
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