Underdogs are already 1-0 in NFL Week 5 after 3-point ‘dogs the Indianapolis Colts overcame the Denver Broncos on Thursday Night Football, but more favorites should be toppled on Sunday and we’ll be trying to locate those upsets in this article. We have found three underdogs that could outperform their odds this weekend, or even be pretty terrible and still cover, as the Colts did!
Let’s take a look at our best underdog bets for Week 5 of the 2022 NFL season.
We have NFL picks for every game on the Week 5 slate