![Texans vs. Colts Prediction, Odds, Pick: NFL Week 1 Texans vs. Colts Prediction, Odds, Pick: NFL Week 1](https://sports.betmgm.com/en/blog/wp-content/uploads/2023/10/nfl-cj-stroud-texans-betmgm.jpg)
It's a rematch of the Week 18 meeting last year that earned Houston the AFC South title. Below, bettors can find my Texans vs. Colts prediction.'
Houston went from worst in the division two years ago to first last season. After earning a playoff win and adding Stefon Diggs, they're amongst the favorites in the Super Bowl odds.'
Considering Indianapolis lost Anthony Richardson after only four games, a 9-8 season last year could be considered a success. With Richardson, they beat Houston by 11 points.'
Here's a look at the NFL betting lines and my prediction for this Week 1 matchup.'
Colts vs. Texans Odds, Week 1
- Houston Texans Moneyline: -135
- Indianapolis Colts Moneyline: +110
- Game Spread: Houston Texans -2.5 (-105)
- Game Over/Under: 48.5 Points (-105/-115)