OddsJam's NFL experts take you through the betting odds, picks and predictions for this matchup between the Tennessee Titans and the Buffalo Bills. This game is set to kick off on September 19, 2022. The Buffalo Bills are at home for this game.
Tennessee Titans vs. Buffalo Bills Betting Odds
The Tennessee Titans visit the Buffalo Bills for this NFL matchup on September 19, 2022. Kickoff for Monday's game is 7:15 p.m. ET / 4:15 p.m. PT.
The Buffalo Bills are favored at -320 moneyline odds on FanDuel. The Tennessee Titans are +260 underdogs on the moneyline in this matchup vs. the Buffalo Bills and +6.5 on the point spread at -102 odds.