We have put together a 4-pick cross-sport parlay that will take you right through Sunday, including picks from the NFL, NHL, NBA, and MLB. One pick is taken from each sport and a winning ticket would give us a very nice payout with odds of +1114 at DraftKings Sportsbook.
NFL pick today: Tennessee Titans -2.5 over Indianapolis Colts (-110), 1:00 pm ET
These AFC South rivals met just 3 weeks ago, when Tennessee won 24-17 and covered a 4-point spread as a road underdog. That gave the Titans, not just their fourth-straight win over Indianapolis, but also the fourth-straight time they had covered the spread – 3 times as a road dog and once as a home favorite.
The key to this matchup is the Colts defense versus Derrick Henry. The Titans are coming off a bye, so they are well-rested. In their first meeting this year, Henry rushed for 114 yards and a touchdown, giving him his 5th 100-yard effort over their last 6 meetings.'Tennessee is all about time of possession and ball control, something they can continue to focus on this game. For that reason, backing the Titans to win and cover will be the play.
Be sure to check out our full Indianapolis Colts vs Tennessee Titans predictions