Steelers vs Colts Prediction, Odds & Best Prop Bets – NFL, Week 12, MNF

The Pittsburgh Steelers (3-7) visit Lucas Oil Stadium to take on the Indianapolis Colts (4-6) on Nov. 28. Kickoff is scheduled for 8:15pm EST in Indianapolis for Monday Night Fooball.

The Colts are betting favorites in Week 12, with the spread sitting at -2.5 (-110).

The Steelers vs. Colts Over/Under is 39.5 total points for the game.

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Steelers vs. Colts Prediction for Week 12

Based on recent trends, the winning team model predicts the Colts will win this Week 12 game with 53.5% confidence.

Based on recent against-the-spread trends, the model predicts the Steelers will cover the spread this Week 12 with 58.0% confidence.

Both predictions factor in up-to-date player injuries for both the Steelers and Colts, plus offensive & defensive matchups, recent games and key player performances this season.


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Best Steelers Player Prop Bets Today

We’ve highlighted some favorite NFL player prop bets for Steelers players for Week 12, looking at profitable historical betting trends:

  • Kenny Pickett has hit the TD Passes Under in his last 5 games (+5.45 Units / 49% ROI)
  • Mitchell Trubisky has hit the Rushing Yards Under in his last 4 games (+4.00 Units / 77% ROI)
  • Pat Freiermuth has hit the Receptions Over in 10 of his last 15 games (+3.95 Units / 21% ROI)
  • Kenny Pickett has hit the Interceptions Under in 4 of his last 5 games (+3.65 Units / 57% ROI)
  • George Pickens has hit the Receptions Over in 3 of his last 4 away games (+2.15 Units / 45% ROI)

Best Colts Player Prop Best Bets Today

And here are some top NFL player prop bets for Colts players for Week 12, looking at profitable historical betting trends:

  • Parris Campbell has hit the Receiving Yards Over in 7 of his last 8 games (+6.00 Units / 68% ROI)
  • Michael Pittman has hit the Receptions Over in 11 of his last 16 games (+5.95 Units / 33% ROI)
  • Jonathan Taylor has hit the Receiving Yards Under in 6 of his last 7 games at home (+4.80 Units / 55% ROI)
  • Parris Campbell has hit the Receptions Over in 6 of his last 8 games (+4.15 Units / 40% ROI)
  • Alec Pierce has hit the Receptions Under in 5 of his last 6 games (+3.75 Units / 43% ROI)

  • The Pittsburgh Steelers have hit the 1H Game Total Over in 8 of their last 10 away games (+6.85 Units / 63% ROI)
  • The Pittsburgh Steelers have covered the 4Q Spread in 12 of their last 18 games (+5.45 Units / 25% ROI)
  • The Pittsburgh Steelers have hit the 1Q Game Total Over in 5 of their last 6 games (+5.20 Units / 76% ROI)
  • The Pittsburgh Steelers have hit the 2Q Game Total Over in 6 of their last 8 games (+4.90 Units / 53% ROI)
  • The Pittsburgh Steelers have hit the 2H Game Total Under in 5 of their last 6 games (+3.90 Units / 60% ROI)

  • The Indianapolis Colts have hit the Game Total Under in 14 of their last 16 games (+11.80 Units / 67% ROI)
  • The Indianapolis Colts have hit the 1H Game Total Under in 13 of their last 16 games (+10.75 Units / 60% ROI)
  • The Indianapolis Colts have hit the Team Total Under in 12 of their last 14 games (+9.50 Units / 60% ROI)
  • The Indianapolis Colts have hit the 1Q Game Total Under in 11 of their last 13 games (+8.60 Units / 53% ROI)
  • The Indianapolis Colts have hit the 3Q Game Total Under in 11 of their last 16 games (+6.45 Units / 35% ROI)

Steelers Against the Spread (ATS) Record

Against the spread this NFL season, the Steelers have gone 4-5 (-1.5 Units / -13.7% ROI).

  • Steelers are 3-7 when betting on the Moneyline for -0.4 Units / -3.72% ROI
  • Steelers are 4-6 when betting the Over for -2.6 Units / -23.64% ROI
  • Steelers are 6-4 when betting the Under for +1.6 Units / ROI

Colts Against the Spread (ATS) Record

Against the spread this NFL season, the Colts have gone 5-6 (-1.45 Units / -12.24% ROI).

  • Colts are 4-6 when betting on the Moneyline for -1.95 Units / -12.38% ROI
  • Colts are 2-9 when betting the Over for -7.9 Units / -65.29% ROI
  • Colts are 9-2 when betting the Under for +6.8 Units / 56.2% ROI

Pittsburgh Steelers: Keys to the Game vs. the Indianapolis Colts

The Steelers are winless (0-6) when allowing an average of more than 5 yards on first down plays this season — tied for worst in NFL; League Avg: .426.

The Steelers are winless (0-5) when committing 1 or more turnovers this season — tied for worst in NFL; League Avg: .400.

The Steelers are winless (0-4) when throwing 2 or more interceptions since the 2021 season — tied for worst in NFL; League Avg: .207.

The Steelers are winless (0-3) vs top 10 run offenses this season — tied for worst in NFL; League Avg: .437.

Indianapolis Colts: Keys to the Game vs. the Pittsburgh Steelers

The Colts are 2-3 (.400) at home this season — tied for 4th-worst in NFL; League Avg: .540.

The Colts were 5-1 (.833) vs bottom 10 run defenses last season — tied for 7th-best in NFL; League Avg: .635.

  
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