Steelers vs Bills NFL predictions, expert picks, odds & spreads
Steelers vs Bills NFL predictions, expert picks, odds & spreads

The Week 5 NFL game between the Pittsburgh Steelers and Buffalo Bills marks a small piece of sports betting history as the Steelers become the final team in the league to be listed as underdogs of 14 points or more since the 1970 merger. The Steelers are 1-3 and their odds reflect the tough task facing them as they go up against the 3-1 Buffalo Bills. A spread as big as this always makes things interesting for bettors, but should you take the huge start with Pittsburgh or trust Buffalo to dominate? Our NFL expert has picks, predictions and best bets for Steelers vs Bills, so let&#821 7;s break it down.

Be sure not to miss any of our NFL picks for Week 5 — we went 13-2-1 on spreads last week!

NFL Week 5 Pittsburgh Steelers vs Buffalo Bills prediction

The Steelers begin a new era for this game as rookie Kenny Pickett makes his first start for the team. Pittsburgh head coach Mike Tomlin opted for experience at the start of the season, giving veteran Mitch Trubisky the first chance to lead his offence, but although the Steelers opened with a surprise win over the Bengals, defeats to the Patriots, Browns and Jets have followed. Trubisky was benched at halftime of last week’s game and gets the chance to start in one of the toughest games possible.

The Bills started the season with wide-margin wins over the Rams and Titans, but have not looked so dominant since, losing in Miami before needing a big comeback to take down the Ravens 23-20 last week. They will need a much bigger win to cover the spread this week, so let’s take a look at the lines for Sunday’s game.

Pittsburgh Steelers vs Buffalo Bills spread, odds & betting lines

  
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