Seattle Mariners at Houston Astros odds, picks and predictions

The Seattle Mariners (54-45) head to Minute Maid Park Thursday to start a 4-game series with the Houston Astros (64-35) in the final series of the year between the AL West rivals. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze Tipico Sportsbook’s lines around the Mariners vs. Astros odds with MLB picks and predictions.

Season series: Houston leads 9-6.

The Mariners rode a 14-game winning streak into the All-Star break before getting swept in a 3-game set by the Astros then bouncing back to sweep the Texas Rangers in a 3-game series Monday-Wednesday.

The Astros won their 1st 5 games after the All-Star break (2 vs. the New York Yankees and 3 vs. the Mariners) before being swept in a 3-game set at the Oakland Athletics this week.

  
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