San Francisco Giants vs. San Diego Padres odds, picks and predictions

The San Francisco Giants (11-14) open a 2-game series against the San Diego Padres (13-14) Saturday at Estadio Alfredo Harp Helu in Mexico City, Mexico. First pitch is scheduled for 6:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting. The Padres recorded a 13-6 record against the Giants in 2022.

The Giants lost 6-0 to the St. Louis Cardinals Thursday. San Francisco had won 5 consecutive games before the loss.

The Padres fell 5-2 to the Chicago Cubs on Thursday. San Diego has tallied a 5-5 record in its last 10 games.

Giants vs. Padres projected starters

  
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