San Francisco Giants at San Diego Padres odds, picks and predictions

The San Francisco Giants (53-55) head down the coast to start a 3-game series with the San Diego Padres (61-50). First pitch from Petco Park is scheduled for 9:40 p.m. ET. Let’s analyze Tipico Sportsbook’s lines around the Giants vs. Padres odds with MLB picks and predictions.

San Francisco is 5-5 straight up (SU) in its last 10 games and swept a 2-game interleague series with the Bay Area neighbor Oakland Athletics Saturday-Sunday after losing 4 straight at home to the Los Angeles Dodgers.

San Diego is also 5-5 SU over its last 10 but has lost 4 consecutive outings, which includes being swept in a 3-game series at the Dodgers this past weekend.

Season series: The Padres lead 6-4 but the Giants have a plus-9 run differential in those meetings (45-36).

  
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