San Francisco Giants at San Diego Padres odds, picks and predictions
San Francisco Giants at San Diego Padres odds, picks and predictions

The San Diego Padres (80-62) welcome the San Francisco Giants (69-72) to Petco Park Friday for the 1st game of a 3-game series. First pitch is set for 9:40 p.m. ET (Apple TV+). Let’s analyze FanDuel Sportsbook’s'lines around the Giants vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 4-3

The Giants beat the Arizona Diamondbacks 3-2 Thursday to avoid a sweep in that series. San Francisco lost 8-7 Tuesday and 6-4 Wednesday and has lost 4 of its last 5 games. It sits 4th in the NL West. The Giants are 29-40 on the road and 66-75 against the spread (ATS).

The Padres lost 4-3 Thursday, missing out on the sweep over the Detroit Tigers. San Diego won the prior 2 games a combined 9-5. It has won 7 of its last 11 and is 2nd in the NL West. The Padres are 39-33 at home, having won 4 of their last 6 home games, and are 72-70 ATS.

Giants at Padres projected starters

  
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