San Francisco Giants at Pittsburgh Pirates odds, picks and predictions
San Francisco Giants at Pittsburgh Pirates odds, picks and predictions

The San Francisco Giants (23-26) and Pittsburgh Pirates (23-26) play the 2nd game of a 3-game series at PNC Park Wednesday. First pitch is scheduled for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s'lines around the Giants vs. Pirates odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 2-2

The Giants snapped a 4-game winning streak Tuesday with a 7-6 loss in 10 innings against Pittsburgh while failing to cash as -129 road favorites. San Francisco led 6-2 after 8 innings but allowed 4 runs in the bottom of the 9th and the game-winning run in the 10th. LHP Erik Miller'was credited with the loss.

Pittsburgh has won back-to-back games after taking down San Francisco Tuesday and cashing as a +119 home underdog. Pirates 2B'Nick Gonzalez walked it off in the 10th with a run-scoring single.

Giants at Pirates projected starters

  
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