The Cleveland Guardians (54-31) welcome the San Francisco Giants (43-45) to Progressive Field Friday for the opener of their 3-game series. First pitch is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s'lines around the Giants vs. Guardians odds and make our expert MLB picks and predictions for the best bets.
Season series: First meeting; Giants took 2 of 3 games in 2023
The Giants beat the Atlanta Braves 4-2 Thursday, closing at +111 on the moneyline. They won 2 of 3 in the series and have won 4 of their last 6 games. San Francisco has been awful on the road this season at just 18-26, the 7th-worst road record in the majors. It is 42-46 against the spread (ATS).
The Guardians beat the Chicago White Sox 8-4 at home Thursday, closing as a sizable -214 favorite. They have traded off winning and losing over their last 6 games and are 3-5 straight up over their last 8 games. Cleveland is 7-1 in its last 8 at home and 28-10 at home on the season. It is 48-37 ATS.