San Francisco 49ers vs. Seattle Seahawks odds, tips and betting trends | Week 2
San Francisco 49ers vs. Seattle Seahawks odds, tips and betting trends | Week 2

After losing 19-10 to the Bears in their previous tilt, the San Francisco 49ers (0-1) will host the Seattle Seahawks (0-0), who are coming off a 17-16 victory against the Broncos. The game is slated for 4:05 PM ET on Sunday, September 18.

The 49ers were beaten by the Chicago Bears 19-10 in their last outing. The Seahawks are coming off of a 17-16 win over the Denver Broncos. In that matchup with the Bears, Trey Lance had 164 yards on 13-of-28 passing (46.4%) for the Niners, with no touchdowns and one interception. He also carried the ball 13 times for 54 yards. Deebo Samuel took eight carries for 52 yards (6.5 yards per carry) and one touchdown, while adding two receptions for 14 yards in the passing game. Jauan Jennings had four receptions for 62 yards (15.5 per catch) against the Bears. Geno Smith went 23-for-28 with 195 yards, two touchdowns and no interceptions for the Hawks against the Broncos. Rashaad Penny put together a 12-carry, 60-yard game (5.0 yards per attempt), while also adding two receptions for seven yards . Colby Parkinson picked up 43 yards through the air after two catches (on two targets), with one touchdown.

We give more info below, and that includes how to watch this game on TV.

49ers vs. Seahawks Betting Information

National Football League odds courtesy of Tipico Sportsbook. Odds updated Tuesday at 11:29 PM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread Favorite: 49ers (-10)
  • Moneyline: 49ers (-474), Seahawks (+358)
  • Total: 42.5 Points

  
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