San Francisco 49ers vs. Los Angeles Rams odds, tips and betting trends | Week 4
San Francisco 49ers vs. Los Angeles Rams odds, tips and betting trends | Week 4

Cooper Kupp, who ranks sixth-best in the league in receiving yards, will try to lead the way for the Los Angeles Rams (2-1) on October 3 at 8:15 PM ET, when they visit the San Francisco 49ers (1-2) and their first-ranked pass D (148.3 passing yards allowed per game).

The 49ers enter this matchup after an 11-10 loss to the Denver Broncos in their most recent outing. Last time out, the Rams deefated the Arizona Cardinals 20-12. Against the Broncos, Jimmy Garoppolo led the Niners with 211 yards on 18-of-29 passing (62.1%) for one touchdown and one interception. Jeff Wilson Jr. took 12 carries for 75 yards (6.3 yards per carry), while adding three receptions for 31 yards in the passing game. Deebo Samuel had five receptions for 73 yards (14.6 per catch) against the Broncos. Matthew Stafford threw for 249 yards for the Rams against the Cardinals, going 18-for-25 (72.0%) with no touchdowns and no interceptions. Cam Akers put together a 12-carry, 61-yard game (5.1 yards per attempt) with one touchdown. Ben Skowronek caught four passes for 66 yards (16.5 yards per catch).

We will dive into all of the details about this contest, including how to watch on TV.

49ers vs. Rams Betting Information

National Football League odds courtesy of Tipico Sportsbook. Odds updated Monday at 11:30 PM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread Favorite: 49ers (-2.5)
  • Moneyline: 49ers (-142), Rams (+120)
  • Total: 42.5 Points

  
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