San Francisco 49ers vs Houston Texans Prediction, 8/25/2022 NFL Picks, Best Bets & Odds Preseason Week 3
The Houston Texans (4-13 last year) will try to beat the San Francisco 49ers (10-7 last season) at NRG Stadium on Thursday. San Francisco opens this matchup as 3-point favorites. The betting total is set at 41. This report includes betting predictions and our expert NFL picks for todays game.

  
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