OddsJam's NFL experts take you through the betting odds, picks and predictions for this matchup between the San Francisco 49ers and the Chicago Bears. This game is set to kick off on September 11, 2022. The Chicago Bears are at home for this game.
San Francisco 49ers vs. Chicago Bears Betting Odds
The San Francisco 49ers visit the Chicago Bears for this NFL matchup on September 11, 2022. Kickoff for Sunday's game is 1:00 p.m. ET / 10:00 a.m. PT.
The San Francisco 49ers are favored at -310 moneyline odds on FanDuel. The Chicago Bears are +250 underdogs on the moneyline in this matchup vs. the San Francisco 49ers and +6.5 on the point spread at -102 odds.