The San Francisco 49ers (2-2), who grabbed a win against the Rams in their last game, visit the Carolina Panthers (1-3) at Bank of America Stadium on October 9 at 4:05 PM ET. The Panthers were defeated by the Cardinals in their last game.
The 49ers enter the matchup after winning 24-9 over the Los Angeles Rams in their last outing on October 3. Last time out, the Panthers lost 26-16 to the Arizona Cardinals. Against the Rams, Jimmy Garoppolo led the Niners with 239 yards on 16-of-27 passing (59.3%) for one touchdown and no interceptions. Jeff Wilson Jr. totaled 74 rushing yards on 18 carries (4.1 yards per carry), scoring one touchdown on the ground. Deebo Samuel had six receptions for 115 yards (19.2 per catch) and one touchdown against the Rams. Baker Mayfield went 22-for-36 with 197 yards, one touchdown and two interceptions for the Panthers against the Cardinals. Christian McCaffrey carried the ball eight times for 27 yards. He caught nine passes for 81 yards and one touchdown. D.J. Moore recorded six catches for 50 yards (on 11 targets).
We dig deep into all of the details you need before this contest starts in this article, including how to watch on TV.
49ers vs. Panthers Betting Information
National Football League odds courtesy of Tipico Sportsbook. Odds updated Tuesday at 11:28 PM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
- Spread Favorite: 49ers (-6.5)
- Moneyline: 49ers (-274), Panthers (+221)
- Total: 39 Points