To kick off the 2022 NFL season, the San Francisco 49ers (0-0) are on the road to face the Chicago Bears (0-0) in an early game Sunday. Kickoff is at 1 p.m. ET at Soldier Field, and the game will air regionally on FOX. Below, we analyze Tipico Sportsbook’s lines around the 49ers vs. Bears odds, and make our expert NFL picks and predictions.
The 49ers are coming off a 10-win season, a trip to the playoffs and an appearance in the NFC Championship Game. The difference is that this year their starting quarterback will be 2021 No. 3 overall pick'Trey Lance. Lance takes over for'Jimmy Garoppolo, who remains on the team as a backup.
The Bears hired coach Matt Eberflus'to groom second-year QB Justin Fields'to be a franchise quarterback and get the team back to the postseason after a 6-11 2021 season.
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