The New Orleans Saints and Los Angeles Rams kick off the Week 16 slate on Thursday Night Football in a crucial game for each team's playoff hopes, and we have you covered with our Saints vs. Rams predictions for Thursday Night Football based on the best NFL odds.
Entering the final three weeks of the 2023 NFL regular season, the New Orleans Saints (7-7) and Los Angeles Rams (7-7) can't afford to slip up if they want to preserve their shot at a dark-horse Super Bowl run. Those dreams will take a massive hit for one side on Thursday Night Football to kick off the Week 16 schedule.
The Rams have looked like a different team since a Week 10 bye, winning four of five games to roar back into the NFC wild-card picture. The Saints are still eyeing a potential division title after winning two straight games to sit in a tie atop the NFC South standings entering Week 16.
To go along with our NFL Week 16 odds, here is our best Saints vs. Rams prediction for Thursday Night Football (odds via our best NFL betting sites; pick confidence based on a 1-to-5-star scale).
Saints vs. Rams prediction: Thursday Night Football
For the first time in three weeks, we won't be subjected to backup QBs dueling under the bright lights of Thursday Night Football. That said, not every starter is built the same.
Rams starter Matthew Stafford has been on a heater over the last four weeks, leading the league in touchdown passes (12) while ranking in the top five in passing yards (265 YPG) and big-time throws (nine).
He's also tossed just one interception during that stretch – the fewest of any full-time starter – and his 112.6 passer rating ranks behind only NFL MVP odds favorite Brock Purdy among qualified starters.
Saints QB Derek Carr looked sharp last week (218 yards, 3 TDs) against the lowly New York Giants, which marked his first game without an INT in over a month. Still, he's struggled to elevate this offense against competent defenses, especially as he plays through various injuries.
He'll be tested this week if Chris Olave (ankle) joins Michael Thomas (knee) on the inactive list, which seems likely on a short week. New Orleans' run game has been a mess, too, and faces a Rams front allowing the NFL's fifth-fewest rushing yards (89.2 YPG) since a Week 10 bye.
The biggest mismatch comes on the other side. The Saints' run defense has been a strength for years but has been gashed at times in 2023, especially over the back half of the season. They'll have hands full against emerging star Kyren Williams, who leads the league in rushing yards per game (95.3) and success rate (59.7%) and is averaging 131 yards over his las t five games.
Fittingly, the Rams are 4-0 ATS since Williams returned from a midseason injury, and they're 2-0 ATS this season when laying at least four points. Expect both streaks to continue on Thursday.
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Saints vs. Rams best odds
| DraftKings | FanDuel | BetMGM | Caesars | bet365 |
|---|---|---|---|---|
| Rams -4 | Rams -4 | Rams -4 | Rams -4 | Rams -4 |
| -110 | -110 | -110 | -110 | -110 |
As you can see above, the market is in full consensus on this game with the Rams dealing as 4-point favorites with -110 odds across our best sports betting apps.
We've highlighted the odds at BetMGM for this wager, but ultimately, this comes down to your personal preference on which book to use. It's worth checking out our best sportsbook promos to make sure you're getting the most out of whichever book you choose.
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Saints vs. Rams odds for Thursday Night Football
Saints vs. Rams odds a nalysis
The Rams opened anywhere from -3 to -3.5 across our best sports betting sites, and we've already seen a strong move toward the home favorites, who are now trading at -4 at all of our best sportsbooks. Roughly 96% of the early money is backing L.A., though we'll obviously see a more logical split as kickoff nears.
We haven't seen any movement on the betting total, which opened at 44.5 and remains there early in the week. If you're eyeing the Under, FanDuel has the best price at -105.
Thursday Night Football game info
- When: Thursday, Dec. 21 at 8:15 p.m. ET
- Where: SoFi Stadium, Inglewoood, CA
- How to watch: Amazon Prime Video
- Weather: Indoors
Saints-Rams prediction made Monday at 3:30 p.m. ET
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