Saints vs 49ers Prediction, Odds & Best Prop Bets – NFL, Week 12

The New Orleans Saints (4-7) visit Levi’s Stadium to take on the San Francisco 49ers (6-4) on Nov. 27. Kickoff is scheduled for 4:25pm EST in Santa Clara.

The 49ers are betting favorites in Week 12, with the spread sitting at -9.5 (-110).

The Saints vs. 49ers Over/Under is 43 total points for the game.

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Saints vs. 49ers Prediction for Week 12

Based on recent trends, the winning team model predicts the 49ers will win this Week 12 game with 80.0% confidence.

Based on recent against-the-spread trends, the model predicts the 49ers will cover the spread this Week 12 with 54.0% confidence.

Both predictions factor in up-to-date player injuries for both the Saints and 49ers, plus offensive & defensive matchups, recent games and key player performances this season.


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Best Saints Player Prop Bets Today

We’ve highlighted some favorite NFL player prop bets for Saints players for Week 12, looking at profitable historical betting trends:

  • Mark Ingram has hit the Rushing Yards Under in 8 of his last 10 games (+5.25 Units / 41% ROI)
  • Mark Ingram has hit the Receiving Yards Under in his last 5 games (+5.00 Units / 77% ROI)
  • Alvin Kamara has hit the Receiving Yards Under in 6 of his last 7 away games (+4.80 Units / 55% ROI)
  • Taysom Hill has hit the Interceptions Under in his last 4 games (+4.55 Units / 78% ROI)
  • Jarvis Landry has hit the Receptions Under in 7 of his last 10 games (+4.20 Units / 29% ROI)

Best 49ers Player Prop Best Bets Today

And here are some top NFL player prop bets for 49ers players for Week 12, looking at profitable historical betting trends:

  • Jimmy Garoppolo has hit the Completions Under in 11 of his last 16 games (+4.80 Units / 22% ROI)
  • George Kittle has hit the Receptions Under in 12 of his last 18 games (+4.45 Units / 17% ROI)
  • Christian McCaffrey has hit the Receiving Yards Over in his last 4 games at home (+4.00 Units / 84% ROI)
  • Jauan Jennings has hit the Receiving Yards Over in 5 of his last 6 games at home (+3.95 Units / 60% ROI)
  • Deebo Samuel has hit the Receptions Under in 12 of his last 18 games (+3.90 Units / 15% ROI)

  • The New Orleans Saints have hit the 2H Moneyline in 10 of their last 16 games (+5.30 Units / 24% ROI)
  • The New Orleans Saints have hit the 2Q Moneyline in 10 of their last 17 games (+4.95 Units / 23% ROI)
  • The New Orleans Saints have hit the 2H Game Total Over in 8 of their last 12 games (+4.60 Units / 34% ROI)
  • The New Orleans Saints have hit the 4Q Game Total Over in 8 of their last 12 games (+4.55 Units / 34% ROI)
  • The New Orleans Saints have scored last in 11 of their last 17 games (+4.50 Units / 22% ROI)

  • The San Francisco 49ers have hit the Game Total Under in 13 of their last 18 games (+7.50 Units / 38% ROI)
  • The San Francisco 49ers have hit the 1H Game Total Over in their last 6 games (+6.00 Units / 92% ROI)
  • The San Francisco 49ers have hit the 2H Game Total Under in 9 of their last 13 games (+5.50 Units / 37% ROI)
  • The San Francisco 49ers have covered the Spread in 12 of their last 18 games (+5.45 Units / 27% ROI)
  • The San Francisco 49ers have hit the 1Q Game Total Under in 11 of their last 18 games (+5.10 Units / 25% ROI)

Saints Against the Spread (ATS) Record

Against the spread this NFL season, the Saints have gone 4-7 (-3.7 Units / -30.58% ROI).

  • Saints are 4-7 when betting on the Moneyline for -3.3 Units / -22.84% ROI
  • Saints are 6-5 when betting the Over for +0.5 Units / 4.13% ROI
  • Saints are 5-6 when betting the Under for -1.6 Units / ROI

49ers Against the Spread (ATS) Record

Against the spread this NFL season, the 49ers have gone 5-5 (-0.5 Units / -4.57% ROI).

  • 49ers are 6-4 when betting on the Moneyline for -0.75 Units / -3.19% ROI
  • 49ers are 4-6 when betting the Over for -2.6 Units / -23.64% ROI
  • 49ers are 6-4 when betting the Under for +1.6 Units / 14.55% ROI

New Orleans Saints: Keys to the Game vs. the San Francisco 49ers

The Saints are 2-7 (.222) when converting less than 50% of third down conversion opportunities this season — tied for 4th-worst in NFL; League Avg: .411.

The Saints are winless (0-4) when converting less than 55% of its red zone chances into touchdowns this season — tied for worst in NFL; League Avg: .447.

The Saints are winless (0-2) when the opposing team converts 55% or more of its red zone chances into touchdowns this season — tied for worst in NFL; League Avg: .436.

The Saints are 2-6 (.250) when committing 1 or more turnovers this season — tied for 8th-worst in NFL; League Avg: .400.

San Francisco 49ers: Keys to the Game vs. the New Orleans Saints

The 49ers are 5-2 (.714) when forcing 1 or more turnovers this season — 10th-best in NFL. The Saints have turned the ball over 19 times this season — tied for most in NFL.

  
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