The 6-4 San Francisco 49ers have won three straight and welcome the 4-7 New Orleans Saints. Can the Saints upset the heavily favored Niners? Read on for our best Saints-49ers picks.
The 49ers are feeling good, coming off a third straight win to improve to 6-4. After a slow start, they're now in the NFC West driver's seat and appear to be one of the league's most dangerous teams.
The Saints continue to look awful, but they did just pick up their fourth season win in 10 games. That was over the Los Angel es Rams, though, and we already know the adversity that franchise has faced.
Here are our Saints-49ers Week 12 NFL picks (odds via PointsBet, FanDuel Sportsbook and DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).
Saints vs. 49ers Game Info
- Date: Sunday, Nov. 27, 4:25 p.m. ET
- TV: FOX
- Location: Levi's Stadium, Santa Clara, CA
- Weather: 62 degrees, 0% of precipitation, 8-mph NW winds