Kyle Shanahan will look to extend his positive record against the Rams on Sunday as the 49ers head to Los Angeles for a divisional matchup.'
The Rams have started the season 0-2 and find themselves amidst an injury crisis. Both Cooper Kupp and Puka Nacua are lost for this game as are a number of offensive linemen.'
That makes Los Angeles sizable underdogs against the 49ers, who fell to the Vikings in Week 2.'
With Kyle Shanahan, San Francisco is 10-4 SU against Los Angeles, including 9-0 behind either Brock Purdy or Jimmy Garappolo.'