The Los Angeles Rams (2-1) visit Levi’s Stadium to take on the San Francisco 49ers (1-2) on Oct. 3. Kickoff is scheduled for 8:15pm EDT in Santa Clara.
The 49ers are betting favorites in Week 4, with the spread sitting at -2.5 (-110).
The Rams vs. 49ers Over/Under is 41.5 total points for the game.
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Rams vs. 49ers Prediction for Week 4
Based on recent trends, the winning team model predicts the 49ers will win this Week 4 game with 62.3% confidence.
Based on recent against-the-spread trends, the model predicts the 49ers will cover the spread this Week 4 with 55.0% confidence.
Both predictions factor in up-to-date player injuries for both the Rams and 49ers, plus offensive & defensive matchups, recent games and key player performances this season.
Best Rams Player Prop Bets Today
We’ve highlighted some favorite NFL player prop bets for Rams players for Week 4, looking at profitable historical betting trends:
- Allen Robinson has hit the Receptions Under in 9 of his last 10 games (+7.45 Units / 48% ROI)
- Van Jefferson has hit the Receptions Under in 11 of his last 14 games (+7.10 Units / 33% ROI)
- Matthew Stafford has hit the Interceptions Over in 14 of his last 21 games (+6.85 Units / 28% ROI)
- Cooper Kupp has hit the Receiving Yards Over in 14 of his last 21 games (+5.80 Units / 23% ROI)
- Darrell Henderson has hit the Receiving Yards Under in 8 of his last 12 games (+2.90 Units / 19% ROI)
Best 49ers Player Prop Best Bets Today
And here are some top NFL player prop bets for 49ers players for Week 4, looking at profitable historical betting trends:
- Jimmy Garoppolo has hit the Completions Under in 12 of his last 15 games (+8.50 Units / 44% ROI)
- Deebo Samuel has hit the Receptions Under in 14 of his last 19 games (+7.00 Units / 25% ROI)
- George Kittle has hit the Receptions Under in 11 of his last 15 games (+6.05 Units / 28% ROI)
- Jimmy Garoppolo has hit the Rushing Yards Under in 8 of his last 10 games (+5.25 Units / 42% ROI)
- Jimmy Garoppolo has hit the Interceptions Over in 10 of his last 15 games (+4.90 Units / 28% ROI)
Rams Betting Trends: ATS, Moneyline, Over/Under
- The Los Angeles Rams have hit the Moneyline in 11 of their last 13 games (+9.15 Units / 28% ROI)
- The Los Angeles Rams have hit the 1H Game Total Under in 10 of their last 11 games (+8.90 Units / 74% ROI)
- The Los Angeles Rams have hit the 1Q Game Total Under in 14 of their last 20 games (+7.45 Units / 34% ROI)
- The Los Angeles Rams have scored first in 9 of their last 11 games (+6.55 Units / 42% ROI)
- The Los Angeles Rams have hit the 3Q Game Total Over in 10 of their last 14 games (+6.55 Units / 40% ROI)
49ers Betting Trends: ATS, Moneyline, Over/Under
- The San Francisco 49ers have hit the 1Q Game Total Under in 10 of their last 11 games (+9.05 Units / 74% ROI)
- The San Francisco 49ers have hit the Game Total Under in 10 of their last 11 games (+8.90 Units / 74% ROI)
- The San Francisco 49ers have hit the 1H Game Total Under in 8 of their last 9 games (+8.00 Units / 80% ROI)
- The San Francisco 49ers have covered the Spread in 11 of their last 15 games (+6.75 Units / 41% ROI)
- The San Francisco 49ers have covered the 1H Spread in 11 of their last 15 games (+6.70 Units / 41% ROI)
Rams Against the Spread (ATS) Record
Against the spread this NFL season, the Rams have gone 1-2 (-1.2 Units / -36.92% ROI).
- Rams are 2-1 when betting on the Moneyline for +1 Units / 12.99% ROI
- Rams are 1-2 when betting the Over for -1.2 Units / -36.36% ROI
- Rams are 2-1 when betting the Under for +0.9 Units / ROI
49ers Against the Spread (ATS) Record
Against the spread this NFL season, the 49ers have gone 1-2 (-1.2 Units / -36.36% ROI).
- 49ers are 1-2 when betting on the Moneyline for -2.85 Units / -37.25% ROI
- 49ers are 0-3 when betting the Over for -3.3 Units / -100% ROI
- 49ers are 3-0 when betting the Under for +3 Units / 90.91% ROI
Los Angeles Rams: Keys to the Game vs. the San Francisco 49ers
The Rams were 1-4 (.200) vs top 10 defenses last season — tied for 6th-worst in NFL; League Avg: .447.
The Rams were 4-3 (.571) vs top 10 offenses last season — 8th-best in NFL; League Avg: .376.
The Rams are 2-5 (.286) vs top 10 pass defenses since the 2021 season — tied for 10th-worst in NFL; League Avg: .465.
The Rams are 7-4 (.636) since Week 7 of 2021 — tied for 8th-best in NFL; League Avg: .497.